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  About PSE Game is a competitive game offered as part of the Process Systems Engineering Course at Politecnico di Milano by the PSE-Lab. The game is a weekly serious-game. Playing the game is optional: participation is not compulsory and bad performance will not affect the final mark. However, the game deals with several topics encountered in the course, which are part of the final oral exam. The game is designed to provide an...

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  PSE-Lab just published a new paper!   We made long-time and in-depth research on model-based control tools for automated anesthesia in operative rooms which took to the following article on “Biomedical Signal Processing and Control” of Elsevier:   A physiologically-based approach to model-predictive control of anesthesia and analgesia Adriana Savoca, Davide Manca  ...

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    PSE-Lab just published a new paper!   The joint efforts of medical doctors and engineers took to the publication of a new paper on “Clinical Endocrinology” of Wiley:   Different routes and formulations of melatonin in critically ill patients. A pharmacokinetic randomized study Giovanni Mistraletti, Rita Paroni, Michele Umbrello, Bedrana Moro Salihovic, Silvia Coppola, Sara Froio, Elena Finati, Paolo...

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La trasmissione Smart City di Radio 24 ha ospitato il PSE-Lab per parlare di CLARA il robot automatizzato per il controllo dell’anestesia ad anello chiuso. Il conduttore della trasmissione Maurizio Melis ci ha intervistato per capire come CLARA possa modificare lo stato attuale dell’anestesia generale in sala operatoria aggiungendo un controllo predittivo basato su modello che adotti come variabili controllate i parametri...

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A physiological control system for anesthesia delivery   Application of automated control devices in biomedicine is still emergent, but very promising. Currently, anesthesiologists set an initial dose of analgesic/anesthetic for surgical interventions according to their experience and standard protocols, and then make adjustments after patients’ observation. This approach to anesthesia can lead to intermittent and irregular...

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A joint collaboration between Ospedale San Paolo di Milano and PSE-Lab carried to the publication of a new article on Computers and Chemical Engineering. The interested readers can download the PSE-Lab version.   A physiologically-based diffusion-compartment model for transdermal administration – The melatonin case study Adriana Savoca, Giovanni Mistraletti, Davide Manca  ...

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Juan Pablo Gutierrez is a Chemical Engineer and PhD in Engineering. Coming from Argentina, Juan joined the PSE-Lab in September 2017, promoted by the ERASMUS Sustaint-T Program of the European Commission. Aim of his stay is to evaluate the potential of CO2 Enhanced Oil Recovery (CO2 EOR) to be implemented in his home country. His analysis takes into consideration the three pillars of the sustainability. His research background...

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