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A physiological control system for anesthesia delivery   Application of automated control devices in biomedicine is still emergent, but very promising. Currently, anesthesiologists set an initial dose of analgesic/anesthetic for surgical interventions according to their experience and standard protocols, and then make adjustments after patients’ observation. This approach to anesthesia can lead to intermittent and irregular...

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A joint collaboration between Ospedale San Paolo di Milano and PSE-Lab carried to the publication of a new article on Computers and Chemical Engineering. The interested readers can download the PSE-Lab version.   A physiologically-based diffusion-compartment model for transdermal administration – The melatonin case study Adriana Savoca, Giovanni Mistraletti, Davide Manca  ...

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Juan Pablo Gutierrez is a Chemical Engineer and PhD in Engineering. Coming from Argentina, Juan joined the PSE-Lab in September 2017, promoted by the ERASMUS Sustaint-T Program of the European Commission. Aim of his stay is to evaluate the potential of CO2 Enhanced Oil Recovery (CO2 EOR) to be implemented in his home country. His analysis takes into consideration the three pillars of the sustainability. His research background...

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A joint collaboration between the Veterinary department of the University of Milan and the PSE-Lab published a new article on Journal of Theoretical Biology. Till August 17, 2017 you can download a free copy of the article at the following link. The universal link is: http://dx.doi.org/10.1016/j.jtbi.2017.06.028   A physiologically based model for tramadol pharmacokinetics in horses Roberto Andrea Abbiati, Petra Cagnardi,...

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  PSE-Lab published a new article on Industrial and Engineering Chemistry Research:   Enterohepatic Circulation Effect in Physiologically Based Pharmacokinetic Models: The Sorafenib Case Roberto Andrea Abbiati, Davide Manca   Abstract Sorafenib was recently approved by both FDA and EMA for the treatment of unresectable hepatocellular carcinoma (HCC), renal cell carcinoma (RCC), and thyroid cancer (DTC). This paper...

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PSE-Lab has just published a new paper on “Computers and Chemical Engineering” titled: A systematic approach to the optimal design of chemical plants with waste reduction and market uncertainty Piernico Sepiacci, Valentina Depetri, Davide Manca   Abstract The paper presents a methodology for the quantitative assessment of sustainability applied to the design of chemical plants. Specifically, we focus on the economic...

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Il PSE-Lab è lieto di annunciare il corso di formazione permanente: QSP come Quantitative Systems Pharmacology Modellazione di sistemi per la farmacologia quantitativa   Politecnico di Milano, 20-21 Febbraio 2017   QSP è organizzato con il Patrocinio del Politecnico di Milano, AIDIC Associazione Italiana di Ingegneria Chimica e INSTM- Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali. Il corso...

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